| Product Name | FITC Anti-Mouse CD103 Antibody [M290] |
|---|---|
| Description | CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium. |
| Synonyms | Integrin alpha-E, Itgae, Integrin alpha M290, CD103 |
| Host | Rat |
| Source | Rat |
| Clonality | Monoclonal |
| Clone | M290 |
| Conjugate | FITC |
| Isotype | Rat IgG2a |
| Reactivity | Mouse |
| Applications | FC |
| Form | PBS with 0.05% Proclin300, 1% BSA |
| Uniprot | Q60677 |
| Storage | 4°C |
| Supplier | Assay Genie |
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