| Product Name | FOXL2 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to FOXL2 |
| Synonyms | Blepharophimosis antibody; Blepharophimosis epicanthus inversus and ptosis 1 antibody; Blepharophimosis epicanthus inversus and ptosis antibody; BPES 1 antibody; BPES antibody; BPES1 antibody; Epicanthus inversus and ptosis 1 antibody; Forkhead box L2 antibody; Forkhead box protein L2 antibody; Forkhead transcription factor FOXL2 antibody; FOX L2 antibody; FOXL 2 antibody; FOXL2 antibody; FOXL2_HUMAN antibody; PFRK antibody; PINTO antibody; PITUITARY FORKHEAD FACTOR antibody; POF 3 antibody; POF3 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Forkhead box protein L2 protein (116-216AA) |
| Isotype | IgG |
| Target | FOXL2 |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Uniprot | P58012 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. |
| Supplier | Cusabio |
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