| Product Name | FOXP3 Monoclonal Antibody |
|---|---|
| Description | Mouse monoclonal antibody to FOXP3 |
| Synonyms | JM2; AIID; IPEX; PIDX; XPID; DIETER; MGC141961; MGC141963; FOXP3 |
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide conjugated to KLH derived from Human Heme Oxygenase 1. |
| Isotype | IgG1 |
| Target | FOXP3 |
| Specificity | FOXP3 antibody detects endogenous levels of total FOXP3 |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20C. Stable for 12 months from date of receipt. |
| Uniprot | Q9BZS1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells. |
| Supplier | Cusabio |
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