| Product Name | GABA A Receptor _3 Polyclonal Antibody |
|---|---|
| Description | GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. GABRA3 (Gamma-Aminobutyric Acid Type A Receptor Alpha3 Subunit) is a Protein Coding gene. Diseases associated with GABRA3 include Thyrotoxic Periodic Paralysis and Mucopolysaccharidosis Ii. Among its related pathways are Ligand-gated ion channel transport and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include chloride channel activity and GABA-A receptor activity. An important paralog of this gene is GABRA1. |
| Host | Rabbit |
| Immunogen | Synthetic Peptide |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, WB |
| Form | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Uniprot | P34903 |
| Background |
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. GABRA3 (Gamma-Aminobutyric Acid Type A Receptor Alpha3 Subunit) is a Protein Coding gene. Diseases associated with GABRA3 include Thyrotoxic Periodic Paralysis and Mucopolysaccharidosis Ii. Among its related pathways are Ligand-gated ion channel transport and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include chloride channel activity and GABA-A receptor activity. An important paralog of this gene is GABRA1. |
| Supplier | Elabscience |
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