| Product Name | GABA A Receptor Alpha 5 Antibody: PerCP |
|---|---|
| Description | The GABA A Receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2). Recent research shows their usage in investigating side effects of drugs and the effects of learning and memory. Inverse agonists of the Alpha5 subunit may be useful in the treatment of Alzheimer's Disease (3). Mouse Anti-Human GABA A Receptor Alpha5 Monoclonal IgG1 |
| Synonyms | Gamma-aminobutyric acid receptor subunit alpha-5 Antibody, GABA(A) Receptor subunit Alpha-5 Antibody, Gabra5 Antibody |
| Host | Mouse |
| Clone | S415-24 |
| Immunogen | Fusion protein amino acids 368-419 (last cytoplasmic domain before extracellular C-terminus) of human GABA A Receptor Alpha5. |
| Isotype | IgG1 |
| Specificity | Detects ~55kDa. Does not cross-react with GABA A Receptor Alpha2 or other GABA-A Receptors based on KO validation data. |
| Reactivity | Human, Mouse, Rat |
| Applications | ICC, IF, IHC, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.1% sodium azide |
| Gene Id | NP_000801.1. 2558 |
| Uniprot | P31644 |
| Supplier | Stressmarq Biosciences |
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