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|Product Name||GABARAPL2, 1-117aa, Human|
|Background||GABARAPL2, also known as ATG8, is involved in intra Golgi traffic and modulates intra Golgi transport through coupling between NSF activity and SNAREs activation. GABARAPL2 first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Recombinant human GABARAPL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||Gamma-aminobutyric acid receptor-associated protein-like 2, ATG8, ATG8C, GATE-16, GATE16, GEF2|
|AA Sequence||MGSSHHHHHH SSGLVPRGSH MKWMFKEDHS LEHRCVESAK IRAKYPDRVP VIVEKVSGSQ IVDIDKRKYL VPSDITVAQF MWIIRKRIQL PSEKAIFLFV DKTVPQSSLT MGQLYEKEKD EDGFLYVAYS GENTFGF|
|Molecular Weight||27.4 kDa (243aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2mM DTT, 0.1M NaCl.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Purity||> 90% by SDS-PAGE|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Behrends C., et al. (2010) Nature. 466(7302):68-76.
Sengupta A., et al. (2009) J Biol Chem. 284(41):28319-31.
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