GABARAPL2, 1-117aa, Human

Proteins, Recombinant
More Information
Product Name GABARAPL2, 1-117aa, Human
Background GABARAPL2, also known as ATG8, is involved in intra Golgi traffic and modulates intra Golgi transport through coupling between NSF activity and SNAREs activation. GABARAPL2 first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Recombinant human GABARAPL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Synonyms Gamma-aminobutyric acid receptor-associated protein-like 2, ATG8, ATG8C, GATE-16, GATE16, GEF2
Host E.coli
Tag His-tag
Molecular Weight 27.4 kDa (243aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2mM DTT, 0.1M NaCl.
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI NP_009216
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Behrends C., et al. (2010) Nature. 466(7302):68-76.
Sengupta A., et al. (2009) J Biol Chem. 284(41):28319-31.

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