GAD2 Antibody

Category: Antibodies
Catalog
CSB-PA997765
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Product Name GAD2 Antibody
Description Rabbit polyclonal antibody to GAD65
Synonyms 65 kDa glutamic acid decarboxylase antibody; DCE 2 antibody; DCE2 antibody; DCE2_HUMAN antibody; GAD 2 antibody; GAD 65 antibody; GAD-2 antibody; GAD-65 antibody; Gad2 antibody; Glutamate decarboxylase 2 (pancreas) antibody; Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa) antibody; Glutamate decarboxylase 2 antibody; Glutamate Decarboxylase 65 antibody; Glutamate decarboxylase 65 kDa isoform antibody; Glutamic Acid Decarboxylase 2 antibody; Glutamic Acid Decarboxylase 65 antibody; MGC161605 antibody; MGC161607 antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Synthetic peptide of human GAD2
Isotype IgG
Target GAD2
Reactivity Human
Applications ELISA, IHC
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot Q05329
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Supplier Cusabio

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