| Product Name | GADD45B Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to GADD45B |
| Synonyms | GA45B_HUMAN antibody; GADD45 Beta antibody; Gadd45b antibody; GADD45BETA antibody; Growth arrest and DNA damage inducible 45 beta antibody; Growth arrest and DNA damage inducible beta antibody; Growth arrest and DNA damage-inducible gene GADD45; beta antibody; Growth arrest and DNA damage-inducible protein GADD45 beta antibody; Growth arrest and DNA-damage-inducible protein GADD45 beta antibody; MY118 antibody; MYD118 antibody; MYD118; mouse; homolog of antibody; Myeloid differentiation primary response gene antibody; Myeloid differentiation primary response protein MyD118 antibody; Negative growth regulatory protein MyD118 antibody; Negative growth-regulatory protein MyD118 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human GADD45B |
| Isotype | IgG |
| Target | GADD45B |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | O75293 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. |
| Supplier | Cusabio |
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