| Product Name | GADD45GIP1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to GADD45GIP1 |
| Synonyms | 39S ribosomal protein L59 mitochondrial antibody; CKBBP2 antibody; CKbetaBP2 antibody; CKII beta associating protein antibody; CKII beta binding protein 2 antibody; CKII beta-associating protein antibody; CR6 interacting factor 1 antibody; CR6-interacting factor 1 antibody; CRIF1 antibody; G45IP_HUMAN antibody; GADD45G interacting protein 1 antibody; Gadd45gip1 antibody; Growth arrest and DNA damage inducible GADD45G interacting protein antibody; growth arrest and DNA damage inducible, gamma interacting protein 1 antibody; Growth arrest and DNA damage-inducible proteins-interacting protein 1 antibody; MGC4667 antibody; MGC4758 antibody; MRP L59 antibody; p53 responsive gene 6 antibody; p53 responsive gene 6 protein antibody; p53-responsive gene 6 protein antibody; Papillomavirus L2 interacting nuclear protein 1 antibody; Papillomavirus L2-interacting nuclear protein 1 antibody; PLINP 1 antibody; PLINP antibody; PLINP-1 antibody; PLINP1 antibody; PRG6 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from internal of human GADD45GIP1. |
| Isotype | IgG |
| Target | GADD45GIP1 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | Q8TAE8 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. Goernemann J., Virology 303:69-78(2002). Chung H.K., J. Biol. Chem. 278:28079-28088(2003). The MGC Project Team, Genome Res. 14:2121-2127(2004). |
| Supplier | Cusabio |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
