| Product Name | Galactosidase _ Polyclonal Antibody |
|---|---|
| Description | This gene encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene may result in GM1-gangliosidosis and Morquio B syndrome. GLB1 (Galactosidase Beta 1) is a Protein Coding gene. Diseases associated with GLB1 include Gm1-Gangliosidosis, Type I and Gm1-Gangliosidosis, Type Iii. Among its related pathways are Innate Immune System and Glycosaminoglycan degradation. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and galactoside binding. An important paralog of this gene is GLB1L. |
| Synonyms | GLB1, ELNR1, Beta-galactosidase, Acid beta-galactosidase, Lactase, Elastin receptor 1 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human Galactosidase _. |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Uniprot | P16278 |
| Background |
This gene encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene may result in GM1-gangliosidosis and Morquio B syndrome. GLB1 (Galactosidase Beta 1) is a Protein Coding gene. Diseases associated with GLB1 include Gm1-Gangliosidosis, Type I and Gm1-Gangliosidosis, Type Iii. Among its related pathways are Innate Immune System and Glycosaminoglycan degradation. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and galactoside binding. An important paralog of this gene is GLB1L. |
| Supplier | Elabscience |
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