| Product Name | Galectin-3 Monoclonal Antibody |
|---|---|
| Description | Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for _-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis . |
| Synonyms | 35 kDa lectin,CBP 35,CBP35,Gal 3,GAL3,Galactose specific lectin 3,Galactoside binding protein,GALBP,Galectin 3,Galectin-3,GALIG,IgE binding protein,L 31,Laminin binding protein,Lectin L 29,LGALS2,LGALS3,Mac 2 antigen,MAC2 |
| Host | Mouse |
| Clone | 357 |
| Immunogen | Fusion protein of Galectin-3 |
| Isotype | IgG2b |
| Reactivity | Human, Mouse |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P17931 |
| Background | Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for _-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis . |
| Supplier | Elabscience |
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