| Product Name | GAS3 Polyclonal Antibody |
|---|---|
| Description | This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.PMP22 (Peripheral Myelin Protein 22) is a Protein Coding gene. Diseases associated with PMP22 include Neuropathy, Recurrent, With Pressure Palsies and Charcot-Marie-Tooth Disease, Type 1A. Among its related pathways are Neural Crest Differentiation and a6b1 and a6b4 Integrin signaling. An important paralog of this gene is EMP2. |
| Synonyms | PMP22; GAS3; Peripheral myelin protein 22; PMP-22; Growth arrest-specific protein 3; GAS-3 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the C-terminal region of human GAS3 |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | Q01453 |
| Background | This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.PMP22 (Peripheral Myelin Protein 22) is a Protein Coding gene. Diseases associated with PMP22 include Neuropathy, Recurrent, With Pressure Palsies and Charcot-Marie-Tooth Disease, Type 1A. Among its related pathways are Neural Crest Differentiation and a6b1 and a6b4 Integrin signaling. An important paralog of this gene is EMP2. |
| Supplier | Elabscience |
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