Product Name | GC-Globulin |
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Description | An alpha 2 glycoprotein composed of a single polypeptide chain and present in plasma at levels of 20-55 mg/100ml. It functions in the binding and transport of vitamin D and may also play an important role in actin homeostatis since it has been shown to bind monomeric actin. GC Globulin also binds membranes of both circulating B and T lymphocytes. Clinically concentrations are reduced in patients with severe liver diseases. GC Globulin may also play an important role in the mechanism of the osteomalacia that occurs with Itai-Itai disease. |
Molecular Weight | 52,000 Daltons |
Form | Purified, in 20 mM Na-phosphate, pH 7.4, and 150 mM NaCl |
Purity | > 95% by SDS-PAGE |
Storage | 2-8C for immediate use, or at -2°C (aliquot) |
Supplier | ARP |
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