| Product Name | GCK Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to GCK |
| Synonyms | ATP:D-hexose 6-phosphotransferase antibody; FGQTL3 antibody; GCK antibody; GK antibody; GLK antibody; Glucokinase antibody; Hexokinase D pancreatic isozyme antibody; Hexokinase type IV antibody; Hexokinase-4 antibody; Hexokinase-D antibody; HHF3 antibody; HK IV antibody; HK4 antibody; HKIV antibody; HXK4_HUMAN antibody; HXKP antibody; LGLK antibody; MODY2 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human Glucokinase protein (1-300AA) |
| Isotype | IgG |
| Target | GCK |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot | P35557 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage. |
| Supplier | Cusabio |
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