| Product Name | GDA, 1-454aa, Human (Bioactivity Validated) |
|---|---|
| Description | GDA, also known as guanine deaminase, catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human GDA, was expressed in E.coli and purified by conventional chromatography techniques. |
| Synonyms | Guanine deaminase isoform b , CYPIN, GUANASE, NEDASIN, CYPIN,Cytoplasmic PSD95 interactor, D10S105E, GAH, GDA GUAD_HUMAN, Guanase, Guanine aminase, Guanine aminohydrolase, Guanine deaminase, MGC9982, NEDASIN, p51-nedasin, SLC25A16 |
| Host | E. coli |
| Molecular Weight |
66.7kDa (613aa) 25-100KDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | MCAAQMPPLA HIFRGTFVHS TWTCPMEVLR DHLLGVSDSG KIVFLEEASQ QEKLAKEWCF KPCEIRELSH HEFFMPGLVD THIHASQYSF AGSSIDLPLL EWLTKYTFPA EHRFQNIDFA EEVYTRVVRR TLKNGTTTAC YFATIHTDSS LLLADITDKF GQRAFVGKVC MDLNDTFPEY KETTEESIKE TERFVSEMLQ KNYSRVKPIV TPRFSLSCSE TLMGELGNIA KTRDLHIQSH ISENRDEVEA VKNLYPSYKN YTSVYDKNNL LTNKTVMAHG CYLSAEELNV FHERGASIAH CPNSNLSLSS GFLNVLEVLK HEVKIGLGTD VAGGYSYSML DAIRRAVMVS NILLINKVNE KSLTLKEVFR LATLGGSQAL GLDGEIGNFE VGKEFDAILI NPKASDSPID LFYGDFFGDI SEAVIQKFLY LGDDRNIEEV YVGGKQVVPF SSSV |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Gang Yuan, James C. Bin, et al. (1999). J Biol. Chem. 274(12):8175-80 Trautwein-Schult A, et al (2014) J Mol Microbiol Biotechnol. 24(2):67-81 |
| Background | GDA, also known as guanine deaminase, catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human GDA, was expressed in E.coli and purified by conventional chromatography techniques. |
| Supplier | ARP |
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