| Product Name | Ghrelin (rat) |
|---|---|
| Description | Ghrelin (rat) is the endogenous agonist peptide for the ghrelin receptor (growth hormone secretagogue type 1A receptor or GHS-R). Ghrelin (rat) is produced mainly by the stomach, and is linked to inducing appetite and feeding behaviour, with circulating ghrelin levels being highest before a meal and the lowest after. Injections of ghrelin in both humans and rats have been shown to increase food intake in a dose-dependent manner and also to increase motivation to seek out food. |
| Synonyms | 258338-12-4, GH-180, GH180 , GHS-R, GSSFLSPEHQKAQQRKESKKPPAKLQPR, Ghrelin, endogenous agonist, ghrelin receptor, growth hormone secretagogue type 1A |
| Molecular Weight | 3314.83 Da |
| Target | Ghrelin receptors |
| Amino Acid Sequence | GSSFLSPEHQKAQQRKESKKPPAKLQPR |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Cas Number | 258338-12-4 |
| Storage | Store desiccated, frozen and in the dark |
| Notes | Modifications: Ser-3 is n-octanoylated |
| References |
Inu (2001) Ghrelin: an orexigenic and somatotrophic signal from the stomach. Nat.Rev.Neurosci. 2 551 PMID: 11483998Kojima et al (1999) Ghrelin is growth-hormone-releasing acylated peptide from stomach. Nature 402 656 PMID: 10604470Tolle et al (2001) In vivo and in vitro effects of ghrelin/motilin-related peptide on GH secretion in the rat. Neuroendocrinology 73 54 PMID: 11174017 Related areas All peptides >All ghrelin receptor modulators >All endocrinology research categories >All appetite regulation research categories > |
| Supplier | Isca Biochemicals Limited |
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