| Product Name | GIP (1-39) |
|---|---|
| Description | GIP (1-39) is a highly potent insulinotropic peptide, it is the endogenous truncated form of the incretin hormone GIP (Glucose-dependent Insulinotropic Polypeptide, or Gastric Inhibitory Polypeptide), a 42-amino acid peptide released by the K cells of the duodenum and jejunum in response to food intake. GIP (1-39) is more potent at stimulating glucose-dependent insulin secretion from rat pancreatic β-cells than GIP and loss of the incretin effect is an early characteristic of type 2 diabetes |
| Synonyms | endogenous, food intake, 725474-97-5, GH-160, GH160, GIP (1-39), Gastric Inhibitory Polypeptide, Glucose-dependent Insulinotropic Polypeptide, YAEGTFISDYSIAMDKIRQQDFVNWLLAQKGKKSDWKHN, diabetes, insulinotropic |
| Molecular Weight | 4633.2 Da |
| Target | Glucagon and related receptors |
| Amino Acid Sequence | YAEGTFISDYSIAMDKIRQQDFVNWLLAQKGKKSDWKHN |
| Form | Freeze dried solid |
| Purity | >95% By HPLC |
| Cas Number | 725474-97-5 |
| Storage | Store dark, dry and frozen |
| Notes | Modifications: None |
| References |
Xie et al (2004) GIP1-39, a novel Insulinotropic peptide form and aspects on its mechanism of action. Regul.Peptides 121 107 C PMID: 15256280Ji et al (2016) Neuroprotective effects of glucose-dependent insulinotropic polypeptide in Alzheimer€™s disease. Rev. Neurosci. 27(1) 61 PMID: 26351802Hansen et al (2016) N€terminally and C€terminally truncated forms of glucose€dependent insulinotropic polypeptide are high€affinity competitive antagonists of the human GIP receptor. Br. J. Pharmacol. 173 826 PMID: 26572091 Related areas All peptides >All glucagon and related receptor modulators >All endocrinology research categories >All diabetes research categories > |
| Supplier | Isca Biochemicals Limited |
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