| Product Name | GIP_HUMAN[22-51] |
|---|---|
| Description | GIP_HUMAN[22–51] is a potent proatherosclerotic peptide hormone which has a common precursor with glucose-dependent insulinotropic polypeptide (GIP). Chronic infusion of GIP_HUMAN[22–51] into ApoE−/− mice accelerates the development of aortic atherosclerotic lesions and it also increases the serum concentrations of many inflammatory and proatherogenic proteins, and induces IκB-α degradation and nuclear translocation of NF-κB in human vascular endothelial cells and macrophages. GIP_HUMAN[22–51 can also be labelled with 5-carboxyfluorescein and stable isotope labelled, please inquire. |
| Synonyms | EKKEGHFSALPSLPVGSHAKVSSPQPRGPR, GIP_HUMAN[22 -51], GIP_HUMAN[22-51], GL-040 |
| Molecular Weight | 3181.6 Da |
| Target | Glucagon and related receptors |
| Amino Acid Sequence | EKKEGHFSALPSLPVGSHAKVSSPQPRGPR |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: None |
| References |
Masaki et al (2021) GIP_HUMAN[22-51] is a new proatherogenic peptide identified by native plasma peptidomics. Sci Rep 11 14470 https://doi.org/10.1038/s41598-021-93862-w Related dataAll peptides >All glucagon and related receptor modulators >All cardiovascular research categories >All immunology categories > |
| Supplier | Isca Biochemicals Limited |
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