| Product Name | GJB6 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to GJB6 |
| Synonyms | Connexin 30 antibody; Connexin-30 antibody; Cx30 antibody; CXB6_HUMAN antibody; DFNA3 antibody; DFNA3B antibody; DFNB1B antibody; ECTD2 antibody; ectodermal dysplasia 2; hidrotic (Clouston syndrome) antibody; ED2 antibody; EDH antibody; Gap junction beta 6 protein antibody; Gap junction beta-6 protein antibody; gap junction protein; beta 6 (connexin 30) antibody; gap junction protein; beta 6 antibody; Gap junction protein; beta 6; 30kDa antibody; GJB6 antibody; HED antibody; HED2 antibody; NSRD1 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human GJB6 |
| Isotype | IgG |
| Target | GJB6 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | O95452 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. |
| Supplier | Cusabio |
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