| Product Name | GLP-1 (9-36) amide |
|---|---|
| Description | GLP-1 (9-36) amide, or Glucagon-like peptide-1 (9-36) amide, is a glucoregulatory peptide and the human N-terminally truncated major metabolite of glucagon-like peptide GLP-1 (7-36) amide, formed by dipeptidyl peptidase-IV (DPP IV) cleavage. GLP-1 (9-36) amide acts as an antagonist at the human GLP-1 receptor, inhibits hepatic glucose production and is a weak insulinotropic agent. |
| Synonyms | Glucagon-like peptide-1 (9-36) amide |
| Molecular Weight | 3089.4 Da |
| Target | Glucagon and related receptors |
| Amino Acid Sequence | EGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2 |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Cas Number | 161748-29-4 |
| Storage | Store dry, frozen and desiccated |
| Notes | Modifications: C terminal amide |
| References |
Knudsen and Pridal (1996) Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor. Eur. J. Pharmacol. 318(2-3) 429 PMID: 9016935Elahi et al (2008) GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity 16(7) 1501 PMID: 18421270Sathananthan et al (2013) Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, β-Cell Function, and Glucose Metabolism in Nondiabetic Subjects. Diabetes 62(8) 2752 PMID: 23545708 Related areasAll peptides >All glucagon and related receptor modulators >All endocrinology research categories >All diabetes research categories > |
| Supplier | Isca Biochemicals Limited |
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