GluR-1 Polyclonal Antibody

Category: Antibodies
Catalog
E-AB-31552
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Product Name GluR-1 Polyclonal Antibody
Description Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms GRIA1, GLUH1, GLUR1, Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1
Host Rabbit
Immunogen Synthesized peptide derived from human GluR-1 around the non-phosphorylation site of Ser863.
Isotype IgG
Reactivity Human, Mouse, Primate, Rat
Applications ELISA, IF, IHC, WB
Form PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Uniprot P42261
Background Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Supplier Elabscience

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