| Product Name | GM2/GD2 synthase Polyclonal Antibody |
|---|---|
| Description | GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.B4GALNT1 (Beta-1,4-N-Acetyl-Galactosaminyltransferase 1) is a Protein Coding gene. Diseases associated with B4GALNT1 include Spastic Paraplegia 26, Autosomal Recessive and Spastic Paraplegia 26. Among its related pathways are Glycosphingolipid biosynthesis - ganglio series and Metabolism. GO annotations related to this gene include transferase activity and acetylgalactosaminyltransferase activity. An important paralog of this gene is B4GALNT2. |
| Synonyms | B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl)-galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human GM2/GD2 synthase |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | Q00973 |
| Background | GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.B4GALNT1 (Beta-1,4-N-Acetyl-Galactosaminyltransferase 1) is a Protein Coding gene. Diseases associated with B4GALNT1 include Spastic Paraplegia 26, Autosomal Recessive and Spastic Paraplegia 26. Among its related pathways are Glycosphingolipid biosynthesis - ganglio series and Metabolism. GO annotations related to this gene include transferase activity and acetylgalactosaminyltransferase activity. An important paralog of this gene is B4GALNT2. |
| Supplier | Elabscience |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
