| Product Name | GNAZ, 1-355aa, Human |
|---|---|
| Description | Guanine nucleotide-binding protein G(z) subunit alpha, also known as GNAZ, is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. Recombinant human GNAZ protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Synonyms | Guanine nucleotide-binding protein G(z) subunit alpha, G(x) alpha chain, Guanine nucleotide-binding protein G(z) subunit alpha Gz-alpha |
| Host | E. coli |
| Molecular Weight | 17 kDa (152aa) confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGCRQSSEEK EAARRSRRID RHLRSESQRQ RREIKLLLLG TSNSGKSTIV KQMKIIHSGG FNLEACKEYK PLIIYNAIDS LTRIIRALAA LRIDFHNPDR AYDAVQLFAL TGPAESKGEI TPELLGVMRR LWADPGAQAC FSRSSEYHLE DNAAYYLNDL ERIAAADYIP TVEDILRSRD MTTGIVENKF TFKELTFKMV DVGGQRSERK KWIHCFEGVT AIIFCVELSG YDLKLYEDNQ TSRMAESLRL FDSICNNNWF INTSLILFLN KKDLLAEKIR RIPLTICFPE YKGQNTYEEA AVYIQRQFED LNRNKETKEI YSHFTCATDT SNIQFVFDAV TDVIIQNNLK YIGLC |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Gagnon A.W., et al. (1991) Blood. 78:1247-1253 Matsuoka M., et al. (1990) J. Biol. Chem. 265:13215-13220 |
| Background | Guanine nucleotide-binding protein G(z) subunit alpha, also known as GNAZ, is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. Recombinant human GNAZ protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Supplier | ARP |
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