| Product Name | GNGT1, 1-71aa, Human |
|---|---|
| Description | GNGT1, also known as guanine nucleotide-binding protein G(T) subunit gamma-T1, belongs to the G protein gamma family. This protein is involved as a modulator or transducer in various transmembrane signaling systems. It is required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Recombinant human GNGT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Synonyms | Guanine nucleotide-binding protein G(T) subunit gamma-T1, GNG1 |
| Host | E. coli |
| Molecular Weight | 37.1 kDa (344aa) confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMPVINIE DLTEKDKLKM EVDQLKKEVT LERMLVSKCC EEVRDYVEER SGEDPLVKGI PEDKNPFKEL KGGC |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Scherer SW. et al. (1996) Genomics. 35:241-243 Simonds WF. et al. (1991) J Biol Chem. 266:5363-5366. |
| Background | GNGT1, also known as guanine nucleotide-binding protein G(T) subunit gamma-T1, belongs to the G protein gamma family. This protein is involved as a modulator or transducer in various transmembrane signaling systems. It is required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Recombinant human GNGT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Supplier | ARP |
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