| Product Name | Goat anti-AIRE Antibody |
|---|---|
| Synonyms | AIRE; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) ; AIRE1; APECED; APS1; APSI; PGA1 ; autoimmune regulator (APECED protein); autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy); |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | C-KDVDLSQPRKGRKP |
| Molecular Weight | 57.7; 36.5 |
| Target | AIRE |
| Amino Acid Sequence | KDVDLSQPRKGRKP |
| Reactivity | Bovine, Canine, Human, Rat |
| Applications | ELISA, IHC, WB |
| Working Dilutions | Peptide ELISA: antibody detection limit dilution 1:32000. |
| Form | Liquid, in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Diluent Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Reconstitution | WB: Appr. 60kDa in transfected HEK293 lysates (calculated MW of 57.7kDa according to NP_000374.1). Recommended concentration: 0.5-1.0 µg/ml.. IHC: In paraffin embedded Human Thymus shows nuclear staining in select thymocytes. This antibody has been successfully used in IHC on Human: Ströbel P et al. (2014) PMID: 24236644. This antibody has been successfully used in IHC on Pig: Suzuki S et al. (2014) |
| Gene Id | Human GeneIDs: 326 |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| References | Niki S, Oshikawa K, Mouri Y, Hirota F, Matsushima A, Yano M, Han H, Bando Y, Izumi K, Matsumoto M, Nakayama KI, Kuroda N, Matsumoto M. , Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice., J Clin Invest. 2006 May 1;116(5):1292-1301. Epub 2006 Apr 20. , PMID: 16628255 |
| Supplier | Everest Biotech |
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