| Product Name | Goat anti-CCM2 Antibody |
|---|---|
| Synonyms | CCM2; cerebral cavernous malformation 2 ; C7orf22; MGC4067; MGC4607; MGC74868; PP10187 |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | C-KGEKSRDKKAHEK |
| Molecular Weight | 51.4; 48.8; 39.5 |
| Target | CCM2 |
| Amino Acid Sequence | KGEKSRDKKAHEK |
| Reactivity | Bovine, Canine, Human, Mouse, Rat |
| Applications | ELISA, FC, IF, WB |
| Working Dilutions | Peptide ELISA: antibody detection limit dilution 1:128000. |
| Form | Liquid, in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Diluent Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Reconstitution | WB: Approx 45-48kDa band observed in Human Heart lysates and approx.48kDa in Human Cerebral Cortex lysates and in lysates of cell line KNRK (calculated MW of 48.8kDa according to Human NP_113631.1 and 49.8kDa according to Rat NP_001119747.1). Recommended con. Notes: Immunofluorescence: Strong expression of the protein seen in the cytoplasm of U2OS cells. Recommended concentration: 10µg/ml. Flow Cytometry: Flow cytometric analysis of KNRK cells. Recommended concentration: 10ug/ml.< |
| Gene Id | Human GeneIDs: 83605. Non-Human GeneIDs: 216527 (mouse); |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| References | Zawistowski JS, Stalheim L, Uhlik MT, Abell AN, Ancrile BB, Johnson GL, Marchuk DA. , CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis., Hum Mol Genet. 2005 Sep 1;14(17):2521-31. Epub 2005 Jul 21. , PMID: 16037064 [PubMed - indexed for MEDLINE |
| Supplier | Everest Biotech |
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