| Product Name | Goat anti-Desmin Antibody |
|---|---|
| Synonyms | DES; desmin; CMD1I; CSM1; CSM2; FLJ12025; FLJ39719; FLJ41013; FLJ41793; intermediate filament protein |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | C-RDGEVVSEATQQQHE |
| Molecular Weight | 53.5 |
| Target | Desmin |
| Amino Acid Sequence | RDGEVVSEATQQQHE |
| Reactivity | Bovine, Canine, Human, Mouse |
| Applications | ELISA, IHC, WB |
| Working Dilutions | Peptide ELISA: antibody detection limit dilution 1:128000. |
| Form | Liquid, in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Diluent Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Reconstitution | WB: Approx. 55-60kDa band observed in Human and Mouse Skeletal Muscle lysates and in Human Heart lysates (calculated MW of 53.5kDa according to Human NP_001918.3, and Mouse NP_034173.1). Preliminary testing showed a band at approx 60kDa in Rat and Pig Skelet. IHC: Paraffin embedded Human Heart. Recommended concentration: 4-6µg/ml. |
| Gene Id | Human GeneIDs: 1674. Non-Human GeneIDs: 13346 (mouse); 64362 (rat); |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| References | Chen F, Chang R, Trivedi M, Capetanaki Y, Cryns VL., Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis., J Biol Chem. 2003 Feb 28;278(9):6848-53., PMID: 12477713 |
| Supplier | Everest Biotech |
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