| Product Name | Goat anti-Hamartin / TSC1 (isoform 1) Antibody |
|---|---|
| Synonyms | TSC1; hamartin; tuberous sclerosis 1 ; HGNC:12362; KIAA0243; LAM; MGC86987; TSC; tuberous sclerosis 1 protein; tumor suppressor |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | C-QLHIMDYNETHHEH |
| Molecular Weight | 130 |
| Target | Hamartin / TSC1 (isoform 1) |
| Amino Acid Sequence | QLHIMDYNETHHEH |
| Reactivity | Canine, Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Working Dilutions | Peptide ELISA: antibody detection limit dilution 1:128000. |
| Form | Liquid, in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Diluent Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Reconstitution | WB: Approx 150kDa band observed in Human Brain lysates (calculated MW of 130kDa according to NP_000359.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Miloloza et al Hum Mol Genet. 2000 Jul 22;9(12):1. IHC: Paraffin embedded Human Uterus and Liver. Recommended concentration: 3.75µg/ml. |
| Gene Id | Human GeneIDs: 7248. Non-Human GeneIDs: 64930 (mouse); |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| References | Chan JA, Zhang H, Roberts PS, Jozwiak S, Wieslawa G, Lewin-Kowalik J, Kotulska K, Kwiatkowski DJ. , Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation., J Neuropathol Exp Neurol. 2004 Dec;63(12):1236-42. , PMID: 15624760 |
| Supplier | Everest Biotech |
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