| Product Name | Goat anti-MTHFR Antibody |
|---|---|
| Synonyms | MTHFR; 5,10-methylenetetrahydrofolate reductase (NADPH); OTTHUMP00000002367; OTTHUMP00000002368; methylenetetrahydrofolate reductase intermediate form |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | C-NRPTQNARETEAP |
| Molecular Weight | 74.6 |
| Target | MTHFR |
| Amino Acid Sequence | NRPTQNARETEAP |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Working Dilutions | Peptide ELISA: antibody detection limit dilution 1:16000. |
| Form | Liquid, in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Diluent Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Reconstitution | WB: Preliminary experiments gave an approx 28kDa band in Human Brain (Cerebellum), Skeletal Muscle and Placenta lysates after 0.2µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given . IHC: Paraffin embedded Human Spleen. Recommended concentration: 3.75µg/ml. |
| Gene Id | Human GeneIDs: 4524 |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| References | Bethke L, Webb E, Murray A, Schoemaker M, Feychting M, Lönn S, Ahlbom A, Malmer B, Henriksson R, Auvinen A, Kiuru A, Salminen T, Johansen C, Christensen HC, Muir K, McKinney P, Hepworth S, Dimitropoulou P, Lophatananon A, Swerdlow A, Houlston R., Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma., Cancer Epidemiol. Biomarkers Prev. 2008 May 17 (5): 1195-202., PMID: 18483342 |
| Supplier | Everest Biotech |
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