| Product Name | Goat anti-NRF2 (aa445-458) Antibody |
|---|---|
| Synonyms | NFE2L2; nuclear factor (erythroid-derived 2)-like 2; NRF2; HEBP1; NF-E2-related factor 2; NFE2-related factor 2; OTTHUMP00000205251; OTTHUMP00000207980; nuclear factor erythroid 2-related factor 2; nuclear factor, erythroid derived 2, like 2 |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | C-KHSSRLEAHLTRDE |
| Molecular Weight | 67.8; 66.1; 65.4; 64.4; 59.1; 56.1 |
| Target | NRF2 (aa445-458) |
| Amino Acid Sequence | KHSSRLEAHLTRDE |
| Reactivity | Bovine, Canine, Human, Mouse, Porcine, Rat |
| Applications | ELISA, FC, IF, WB |
| Working Dilutions | Peptide ELISA: antibody detection limit dilution 1:64000. |
| Form | Liquid, in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Diluent Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Reconstitution | WB: Approx 70kDa band observed in Human Lung lysates and approx 75kDa in preliminary testing of Mouse and Rat Liver and KNRK, MDCK, and nuclear NIH3T3 cell lysate (calculated MW of 67.8kDa according to NP_006155.2). This molecular weight rate is routinely o. Notes: Immunofluorescence: Strong expression of the protein seen in the cytoplasm and nuclei of U2OS and HeLa cells. Recommended concentration: 10µg/ml. Flow Cytometry: Flow cytometric analysis of HeLa cells. Recommended conc |
| Gene Id | Human GeneIDs: 4780. Non-Human GeneIDs: 18024 (mouse); 83619 (rat); |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| References | Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, Yamamoto M., Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain., Genes Dev. 1999 Jan 1;13(1):76-86., PMID: 9887101 |
| Supplier | Everest Biotech |
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