| Product Name | GORASP2, 1-452aa, Human |
|---|---|
| Description | GORASP2 also known as golgi reassembly-stacking protein 2 plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. It may regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. Recombinant human GORASP2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Golgi reassembly-stacking protein 2 isoform 1, Golgi reassembly-stacking protein 2, isoform 1, GOLPH6, GRASP55, GRS2, p59 |
| Host | E. coli |
| Molecular Weight | 37.6kDa (349aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMGSSQSV EIPGGGTEGY HVLRVQENSP GHRAGLEPFF DFIVSINGSR LNKDNDTLKD LLKANVEKPV KMLIYSSKTL ELRETSVTPS NLWGGQGLLG VSIRFCSFDG ANENVWHVLE VESNSPAALA GLRPHSDYII GADTVMNESE DLFSLIETHE AKPLKLYVYN TDTDNCREVI ITPNSAWGGE GSLGCGIGYG YLHRIPTRPF EEGKKISLPG QMAGTPITPL KDGFTEVQLS SVNPPSLSPP GTTGIEQSLT GLSISSTPPA VSSVLSTGVP TVPLLPPQVN QSLTSVPPMN PATTLPGLMP LPAGLPNLPN LNLNLPAPHI MPGVGLPELV NPGLPPLPSM PPRNLPGIAP LPLPSEFLPS FPLVPESSSA ASSGELLSSL PPTSNAPSDP ATTTAKADAA SSLTVDVTPP TAKAPTTVED RVGDSTPVSE KPVSAAVDAN ASESP |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl (pH 8.0) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Kuo A. et al. (2000) EMBO J. 19:6427-6439. Truschel S.T.et al. (2011) J. Biol. Chem. 286:20125-20129. |
| Background | GORASP2 also known as golgi reassembly-stacking protein 2 plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. It may regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. Recombinant human GORASP2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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