| Product Name | GPR143 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to GPR143 |
| Synonyms | ALBINISM OCULAR TYPE I antibody; G protein coupled receptor 143 antibody; G-protein coupled receptor 143 antibody; GP143_HUMAN antibody; GPR143 antibody; MOA1 antibody; NETTLESHIP FALLS TYPE OCULAR ALBINISM antibody; Ocular albinism type 1 protein antibody; Ocular albinism type 1 protein homolog antibody; Ocular albinism1 Nettleship Falls type antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human G-protein coupled receptor 143 protein (314-404AA) |
| Isotype | IgG |
| Target | GPR143 |
| Reactivity | Human, Rat |
| Applications | ELISA, WB |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Uniprot | P51810 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport. |
| Supplier | Cusabio |
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