Product Name | GPR75 Antibody |
---|---|
Description | Rabbit polyclonal antibody to GPR75 |
Synonyms | G protein coupled receptor 75 antibody; GPR chr2 antibody; Gpr75 antibody; GPR75_HUMAN antibody; GPRchr2 antibody; OTTHUMP00000159608 antibody; Probable G protein coupled receptor 75 antibody; Probable G-protein coupled receptor 75 antibody; WI 31133 antibody; WI31133 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Recombinant human Probable G-protein coupled receptor 75 protein (372-540AA) |
Isotype | IgG |
Target | GPR75 |
Reactivity | Human |
Applications | ELISA, IF, IHC, WB |
Form | Liquid |
Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Uniprot | O95800 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. |
Supplier | Cusabio |
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