| Product Name | GPRC6A Polyclonal Antibody |
|---|---|
| Description | Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritionnal and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids. |
| Synonyms | GPRC6A, G-protein coupled receptor family C group 6 member A, hGPRC6A, G-protein coupled receptor GPCR33, hGPCR33 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human GPRC6A |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, IF, WB |
| Form | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Uniprot | Q5T6X5 |
| Background | Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritionnal and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids. |
| Supplier | Elabscience |
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