| Product Name | GREM1 ELISA kit (Human) |
|---|---|
| Description | This assay has high sensitivity and excellent specificity for detection of Gremlin 1 (GREM1). No significant cross-reactivity or interference between Gremlin 1 (GREM1) and analogues was observed. |
| Synonyms | PIG2; CKTSF1B1; DAND2; IHG-2; DAND2; DRM; Increased in high glucose protein 2; Cell proliferation-inducing gene 2 protein; Cysteine knot superfamily 1, BMP antagonist 1 |
| Method | Sandwich |
| Detection Range | 125-8,000pg/mL |
| Sensitivity | 55pg/mL |
| Target | GREM1 |
| Specificity | This assay has high sensitivity and excellent specificity for detection of Gremlin 1 (GREM1). No significant cross-reactivity or interference between Gremlin 1 (GREM1) and analogues was observed. |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Urine, Tissue Homogenates And Other Biological Fluids |
| Reconstitution | 1.Prepare all reagents, samples and standards; 2.Add 100uL standard or sample to each well.Incubate 2 hours at 37℃; 3.Aspirate and add 100uL prepared Detection Reagent A.Incubate 1 hour at 37℃; 4.Aspirate and wash 3 times; 5.Add 100uL prepared Detection Reagent B.Incubate 30 minutes at 37℃; 6.Aspirate and wash 5 times; 7.Add 90uL Substrate Solution.Incubate 10-20 minutes at 37℃; 8.Add 50uL Stop Solution.Read at 450nm immediately. |
| Uniprot | O60565 |
| Storage | 4°C for 1 month/ -20°C for long-term(within shelf life) |
| Notes | Colormetric |
| References | Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension;Overexpression of Gremlin promotes non-small cell lung cancer progression;Triple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-term prognosis in suspected and proven acute heart failure patients;Triple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-termprognosis in suspected and proven acute heart failure patients;BMPR2 Mutation-independent Mechanisms of Disrupted BMP Signaling in IPAH;GREM1 Is a Key ReCavia (Guinea pig )lator of Synoviocyte Hyperplasia and Invasiveness;The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells.;Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients.;Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial …;Gremlin-1 suppression increases BMP-2-induced osteogenesis of human mesenchymal stem cells;Platelets as a novel source of Gremlin-1: Implications for thrombo inflammation;Gremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulonephritis;Transcriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration;CAF‐derived exosomes transmitted Gremlin‐1 promotes cancer progression and decreases the sensitivity of hepatoma cells to sorafenib; |
| Supplier | Cloud Clone |
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