| Product Name | GRIK1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to GRIK1 |
| Synonyms | EAA3 antibody; EEA3 antibody; Excitatory amino acid receptor 3 antibody; GLR5 antibody; GluR-5 antibody; GluR5 antibody; GluR6 antibody; GluR7 antibody; Glutamate receptor 5 antibody; Glutamate receptor antibody; Glutamate receptor ionotropic kainate 1 antibody; GRIK1 antibody; GRIK1_HUMAN antibody; Human glutamate receptor GLUR5 antibody; ionotropic kainate 1 antibody; OTTHUMP00000096569 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from human GluR5. |
| Isotype | IgG |
| Target | GRIK1 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | P39086 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Ana V. Paternain, J. Neurosci., Jan 2000; 20: 196. Zhao Ren, J. Biol. Chem., Dec 2003; 278: 52700 - 52709. MICHAEL A. ROGAWSKI, Ann. N.Y. Acad. Sci., Apr 2003; 985: 150. Yoshinori Sahara, J. Neurosci., Sep 1997; 17: 6611. |
| Supplier | Cusabio |
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