GRP170 Antibody: PerCP

Antibodies, Monoclonal Antibodies, Stressmarq Biosciences
More Information
Product Name GRP170 Antibody: PerCP
Description Mouse Anti-Human GRP170 Monoclonal IgG2bK
Accession # NP_006389.3
Reactivity Human, Mouse, Rat
Applications ICC/IF, WB
Background GRP170, also known as ORP150, is the largest member of glucose-regulated Antibodys, and acts as a human chaperone Antibody. It is thought to play an important role in Antibody folding and secretion in the ER. Suppression of the Antibody is associated with accelerated apoptosis, therefore having an important cryoprotective role in hypoxia-induced cellular pertubation. This cryopotective role has led to an anti-tumor immune response, which will hopefully lead to therapeutic immunizations against cancers (1). GRP170 has also been shown to bind with dendritic cells and provide the danger signals to induce anti-tumor immune responses (2).
Clone 6E3-2C3
Concentration 1 mg/ml
Conjugate PerCP
Form Purified, in PBS pH7.4, 50% glycerol, 0.1% sodium azide
Gene ID 10525
Host Mouse
Isotype IgG2b
Immunogen Full length GRP170 protein
Intended Use For Research Use Only
Specificity Detects ~170kDa.
SwissProt Q9Y4L1
Synonyms ORP150 Antibody, HSP12A Antibody, Hypoxia up regulated 1 Antibody, Orp150 Antibody, Glucose regulated Antibody 170 Antibody, 150kDa oxygen regulated Antibody Antibody, 150 kDa oxygen regulated protein antibody, 150 kDa oxygen-regulated protein antibody, 1
Working Dilutions WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

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