| Product Name | GUCY1B3 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to GUCY1B3 |
| Synonyms | GC-S-beta-1 antibody; GC-SB3 antibody; GCbeta1 antibody; GCS beta 1 antibody; GCS beta 3 antibody; GCS-beta-1 antibody; GCS-beta-3 antibody; GCYB1_HUMAN antibody; guanylate cyclase 1; soluble; beta 3 antibody; Guanylate cyclase soluble beta 1 chain antibody; Guanylate cyclase soluble subunit beta-1 antibody; Guanylate cyclase soluble subunit beta-3 antibody; GUC1B3 antibody; GUCSB3 antibody; GUCY1B1 antibody; Gucy1b1; antibody; GUCY1B3 antibody; SGC antibody; Soluble guanylate cyclase small subunit antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from human Guanylate Cyclase _. |
| Isotype | IgG |
| Target | GUCY1B1 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | Q02153 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. A. Shimouchi, Am J Physiol Lung Cell Mol Physiol, Nov 1993; 265: 456. Peter Sinnaeve, Circ. Res., Jan 2001; 88: 103. Stephan Thelitz, J. Thorac. Cardiovasc. Surg., May 2004; 127: 1285 - 1292. Richard C. Venema, Am J Physiol Heart Circ Physiol, Jul 2003; 2 |
| Supplier | Cusabio |
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