| Product Name | H10, biotinylated |
|---|---|
| Description | H10, biotinylated is the N-terminal biotinylated version of the anterior gradient 2 (AGR2) binding peptide H10 (MKMQVRIYLV) which was identified by mRNA display from a complex (>1011) library. AGR2 is a cancer-associated protein and increased levels of extracellular AGR2 (eAGR2) have been correlated with poor prognosis in cancer patients, making it a potential biomarker. H10 possesses high affinity binding to AGR2 with a KD of 6.4 nM, and has been used as the capture reagent in an AGR2 ELISA. H10 can also inhibit cancer cell migration in breast and prostate cancer cell lines. |
| Synonyms | Biotin-GGGSGMKMQVRIYLV-OH, GGGSGMKMQVRIYLV, H10, PP-010, biotinylated |
| Molecular Weight | 1822.26 Da |
| Target | Protein-protein interactions |
| Amino Acid Sequence | Biotin-GGGSGMKMQVRIYLV |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: Biotinylated at N terminus |
| References |
Garri et al (2018) Identification, characterization and application of a new peptide against anterior gradient homolog 2 (AGR2). Oncotarget 9(44) 27363 PMID: 29937991 Related areasAll biotin labelled peptides >All protein-protein interaction modulators >All cancer research categories > |
| Supplier | Isca Biochemicals Limited |
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