| Product Name | HAMP Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to Hepcidin-25 |
| Synonyms | Hamp antibody; HEPC antibody; HEPC_HUMAN antibody; Hepc20 antibody; Hepc25 antibody; HEPCIDIN antibody; Hepcidin 20 antibody; Hepcidin 25 antibody; Hepcidin antimicrobial peptide antibody; Hepcidin-20 antibody; Hepcidin25 antibody; HFE2 antibody; HFE2B antibody; LEAP 1 antibody; LEAP-1 antibody; LEAP1 antibody; Liver expressed antimicrobial peptide antibody; Liver-expressed antimicrobial peptide 1 antibody; PLTR antibody; Putative liver tumor regressor antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant protein of human HAMP |
| Isotype | IgG |
| Target | HAMP |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | liquid |
| Diluent Buffer | Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot | P81172 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. |
| Supplier | Cusabio |
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