| Product Name | HAND2 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to HAND2 |
| Synonyms | AI225906 antibody; AI661148 antibody; autonomic nervous system and neural crest derivatives-expressed protein 2 antibody; Basic helix loop helix transcription factor HAND2 antibody; bHLHa26 antibody; Class A basic helix-loop-helix protein 26 antibody; Deciduum antibody; Deciduum heart autonomic nervous system and neural crest derivatives expressed protein 2 antibody; DHAND 2 antibody; dHAND antibody; DHAND2 antibody; Ehand 2 antibody; Ehand2 antibody; FLJ16260 antibody; HAND 2 antibody; Hand2 antibody; HAND2_HUMAN antibody; Heart and neural crest derivatives expressed 2 antibody; Heart and neural crest derivatives expressed protein 2 antibody; heart and neural crest derivatives expressed transcript 2 antibody; heart antibody; Heart- and neural crest derivatives-expressed protein 2 antibody; Hed antibody; Highly similar to dHAND M musculus antibody; MGC125303 antibody; MGC125304 antibody; Th 2 antibody; Th2 antibody; Thing 2 antibody; Thing2 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human Heart- and neural crest derivatives-expressed protein 2 protein (1-217AA) |
| Isotype | IgG |
| Target | HAND2 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot | P61296 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity). |
| Supplier | Cusabio |
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