| Product Name | HDAC4 (Ab-632) Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to HDAC4 (Ab-632) |
| Synonyms | AHO3 antibody; BDMR antibody; EC 3.5.1.98 antibody; HA6116 antibody; HD 4 antibody; HD4 antibody; HDAC 4 antibody; HDAC A antibody; HDAC4 antibody; HDAC4_HUMAN antibody; HDACA antibody; Histone deacetylase 4 antibody; Histone Deacetylase A antibody; KIAA0288 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Peptide sequence around aa. 630~634 (A-Q-S-S-P) derived from Human HDAC4. |
| Isotype | IgG |
| Target | HDAC4 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, WB |
| Form | liquid |
| Diluent Buffer | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | P56524 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Wang AH, et al. (2000) Mol Cell Biol. 20(18): 6904-6912. Grozinger CM, et al. (2000) Proc Natl Acad Sci U S A. 97(14): 7835-7840. |
| Supplier | Cusabio |
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