Hepatitis A virus cellular receptor 1, 22-237aa, Mouse, Baculovirus
| Product Name | Hepatitis A virus cellular receptor 1, 22-237aa, Mouse, Baculovirus |
|---|---|
| Description | HAVCR1, also known as hepatitis A virus cellular receptor 1, belongs to the immunoglobulin superfamily. This protein plays critical roles in regulating immune cell activity especially regarding the host response to viral infection. It is receptor for TIMD4 and acts in kidney injury and repair. HAVCR1 is also involved in allergic response, asthma, and transplant tolerance. Recombinant mouse HAVCR1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Havcr1, TIM-1, Tim1, Timd1, KIM-1 |
| Host | Virus |
| Molecular Weight |
47.5kDa (426aa) 40-57KDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | YVEVKGVVGH PVTLPCTYST YRGITTTCWG RGQCPSSACQ NTLIWTNGHR VTYQKSSRYN LKGHISEGDV SLTIENSVES DSGLYCCRVE IPGWFNDQKV TFSLQVKPEI PTRPPTRPTT TRPTATGRPT TISTRSTHVP TSIRVSTSTP PTSTHTWTHK PEPTTFCPHE TTAEVTGIPS HTPTDWNGTV TSSGDTWSNH TEAIPPGKPQ KNPTKGHHHH HH |
| Tag | His-tag |
| Reactivity | Mouse |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH7.4) containing 0.5mM PMSF and 30% glycerol. |
| Concentration | 0.25 mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Meyers JH., et al. (2005) Nat. Immunol. 6(5):455-464. Santiago C., et al. (2007) Immunity 26(3):299-310. |
| Background | HAVCR1, also known as hepatitis A virus cellular receptor 1, belongs to the immunoglobulin superfamily. This protein plays critical roles in regulating immune cell activity especially regarding the host response to viral infection. It is receptor for TIMD4 and acts in kidney injury and repair. HAVCR1 is also involved in allergic response, asthma, and transplant tolerance. Recombinant mouse HAVCR1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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