| Product Name | HES6 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to HES6 |
| Synonyms | HES6 antibody; BHLHB41 antibody; Transcription cofactor HES-6 antibody; C-HAIRY1 antibody; Class B basic helix-loop-helix protein 41 antibody; bHLHb41 antibody; Hairy and enhancer of split 6 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from N-terminal of human HES6. |
| Isotype | IgG |
| Target | HES6 |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | Q96HZ4 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation By similarity. UniProtKB Q9JHE6 Bae S.-K., Development 127:2933-2943(2000). Vasiliauskas D., Mech. Dev. 98:133-137(2000). Ota T., Nat. Genet. 36:40-45(2004). |
| Supplier | Cusabio |
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