| Product Name | HIF2 alpha Antibody |
|---|---|
| Description | Members of the hypoxia-inducible factor (HIF) family of transcription factors regulate the cellular response to hypoxia (1). HIF2-Alpha is involved in catecholamine homeostasis, vascular remodeling, physiological angiogenesis and adipogenesis. It is overexpressed in many cancerous tissues, but its exact role in tumourprogression remains to be clarified (2). Studies suggest that in the case of non-small cell lung cancer, HIF2-Alpha actually is a promoter of tumor growth and progression in a solid tumor (1). Other data suggests that HIF2-Alpha is an important regulator of innate immunity, and therefore may be useful in the therapeutic target for treating inflammatory disorders and cancer (3). Mouse Anti-Human HIF2 alpha Monoclonal IgG1 |
| Synonyms | ECYT4 Antibody, EPAS1 Antibody, HIF2alpha Antibody, HIF1 Alpha like factor Antibody, HLF Antibody, Hypoxia inducible factor 2 alpha Antibody, MOP2 Antibody, PASD2 Antibody |
| Host | Mouse |
| Clone | EP190B |
| Immunogen | GST-human EPAS-1 (HIF2alpha) amino acids 535-631 fusion protein |
| Isotype | IgG1 |
| Specificity | Detects ~100kDa. Specific for HIF2 Alpha. |
| Reactivity | Human, Mouse |
| Applications | AM, ELISA, ICC, IF, IHC, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_001421.4. 2034 |
| Uniprot | Q99814 |
| Supplier | Stressmarq Biosciences |
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