| Product Name | Histatin 3 |
|---|---|
| Description | Histatin 3 is a 32 amino acid histidine-rich peptide found in human saliva. Histatins function as antimicrobial peptides and are important components of the innate immune system. Histatin 3 has broad spectrum antimicrobial action including activity against gram positive and gram negative bacteria, fungi including Candida albicans and against the human protozoan parasite Leishania. Histatin 3 is post-translationally cleaved to form Histatin 5 and Histatin 8 |
| Synonyms | AM-090, AM090, DSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN, H-DSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN-OH, Histatin 3, antimicrobial, innate immune system |
| Molecular Weight | 4062.4 Da |
| Target | Antibacterials,Antifungals |
| Amino Acid Sequence | DSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Storage | Store desiccated, frozen and in the dark |
| Notes | Modifications: None |
| References |
Fitzgerald et al (2003) Binding, internalisation and degradation of histatin 3 in histatin-resistant derivatives of Candida albicans. FEMS Microbiol. Lett. 220(2) 247 PMID: 12670688Oudhoff et al (2008) Histatins are the major wound-closure stimulating factors in human saliva as identified in a cell culture assay. FASEB J. 22(11) 3805 PMID: 18650243Hemadi et al (2017) Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment. Int. J. Oral Sci.9, e1 PMID: 29125139 Related areas All antimicrobial peptides >All antifungal agents >All immunology research categories > |
| Supplier | Isca Biochemicals Limited |
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