| Product Name | HOXB13, 1-284aa, Human |
|---|---|
| Description | HOXB13 is a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. Recombinant human HOXB13 protein, fused to His-tag at N-terminus, was expressed in E.coli |
| Synonyms | Homeobox B13, PSGD |
| Host | E. coli |
| Molecular Weight | 38.3 kDa(339aa) confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMEPGNYA TLDGAKDIEG LLGAGGGRNL VAHSPLTSHP AAPTLMPAVN YAPLDLPGSA EPPKQCHPCP GVPQGTSPAP VPYGYFGGGY YSCRVSRSSL KPCAQAATLA AYPAETPTAG EEYPSRPTEF AFYPGYPGTY QPMASYLDVS VVQTLGAPGE PRHDSLLPVD SYQSWALAGG WNSQMCCQGE QNPPGPFWKA AFADSSGQHP PDACAFRRGR KKRIPYSKGQ LRELEREYAA NKFITKDKRR KISAATSLSE RQITIWFQNR RVKEKKVLAK VKNSATP |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | >85 % by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Zeltser L, Desplan C,. et al. (1996). Development 122 (8): 2475–84. Stelnicki EJ, Arbeit J,. et al. (1998). J Invest Dermatol 111 (1): 57–63. |
| Background | HOXB13 is a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. Recombinant human HOXB13 protein, fused to His-tag at N-terminus, was expressed in E.coli |
| Supplier | ARP |
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