| Product Name | Hp Antibody, HRP conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against Haptoglobin conjugated to HRP |
| Synonyms | Hp antibody; Ba1-647 antibody; Haptoglobin antibody; Liver regeneration-related protein LRRG173) [Cleaved into: Haptoglobin alpha chain; Haptoglobin beta chain] antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | HRP |
| Immunogen | Recombinant rat Haptoglobin protein (19-346AA) |
| Isotype | IgG |
| Target | Hp |
| Reactivity | Rat |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | P06866 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway?.Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens. |
| Supplier | Cusabio |
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