| Product Name | HSBP1 (Heat shock factor binding protein 1), Human, Recombinant |
|---|---|
| Description | Heat shock factor binding protein 1 (HSBP1) is a 76 amino acid protein that binds to heat shock factor 1(HSF1), which is a transcription factor involved in the HS response. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulated HSF1 DNA-binding activity. This protein was overexpressed in E.coli and was purified to apparent homogeneity by using conventional column chromatography techniques. |
| Synonyms | NPC-A-13, HSF1BP, Nasopharyngeal carcinoma-associated antigen 13, NPC-A-13, Heat shock factor-binding protein 1, Heat shock factor binding protein 1, Nasopharyngeal carcinoma associated antigen 13, NPC A 13, NPCA 13, |
| Host | E. coli |
| Molecular Weight | 40.2 kDa (349 aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MAETDPKTVQ DLTSVVQTLL QQMQDKFQTM SDQIIGRIDD MSSRIDDLEK NIADLMTQAG VEELESENKI PATQKS |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20 mM Tris-HCl buffer (pH 8.0) |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Morimoto,R.I., et al. (1997) Essays Biochem. 32,17-29. Satyal,S.H., et al. (1998) Genes Dev. 12(13) 1962-1974. |
| Background | Heat shock factor binding protein 1 (HSBP1) is a 76 amino acid protein that binds to heat shock factor 1(HSF1), which is a transcription factor involved in the HS response. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulated HSF1 DNA-binding activity. This protein was overexpressed in E.coli and was purified to apparent homogeneity by using conventional column chromatography techniques. |
| Supplier | ARP |
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