| Product Name | HSD17B12 Antibody, Biotin conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against HSD17B12 conjugated to Biotin |
| Synonyms | 12,3-ketoacyl-CoA reductase,short chain antibody; 17 beta HSD 12 antibody; 17 beta hydroxysteroid dehydrogenase 12 antibody; 17-@beta-HSD XII antibody; 17-@beta-hydroxysteroid dehydrogenase XII antibody; 17-beta-HSD 12 antibody; 17-beta-hydroxysteroid dehydrogenase 12 antibody; 17beta HSD type 12 antibody; 3 ketoacyl CoA reductase antibody; 3-ketoacyl-CoA reductase antibody; DHB12_HUMAN antibody; Estradiol 17 beta dehydrogenase 12 antibody; Estradiol 17-beta-dehydrogenase 12 antibody; HSD17B12 antibody; Hydroxysteroid (17-beta) dehydrogenase 12 antibody; KAR antibody; KIK-I antibody; Kik1 antibody; SDR12C1 antibody; Short chain dehydrogenase/reductase family 12C member 1 antibody; Steroid dehydrogenase homolog antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant human Very-long-chain 3-oxoacyl-CoA reductase protein (40-181AA) |
| Isotype | IgG |
| Target | HSD17B12 |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q53GQ0 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation. |
| Supplier | Cusabio |
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